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Ardour in antibody–drug conjugates (ADCs) is selecting up after a flurry of approvals, numerous mega-deals — at the side of the $43 billion acquisition of Seagen by Pfizer — and some promising original scientific data. In Would maybe well also, ADC specialist ImmunoGen printed sure data from a share 3 trial of Elahere (mirvetuximab soravtansine) when put next with chemotherapy in patients with folate receptor-sure ovarian most cancers. In the 453-patient trial, which integrated ladies whose cancers were already proof towards chemotherapy, median survival used to be 16.5 months with Elahere, when put next with 12.8 months in the chemotherapy arm, representing a 33% good deal in the risk of tumor development or dying. The corporate says it is the first drug to ticket an total survival earnings on this patient population.
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ADCs’ revival.
Nat Biotechnol 41, 740 (2023). https://doi.org/10.1038/s41587-023-01836-2
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DOI: https://doi.org/10.1038/s41587-023-01836-2
